Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DET0867Hydrogenase, group 4, EchE subunit, putative; Identified by similarity to GP:3005971. (359 aa)    
Predicted Functional Partners:
DET0862
Hydrogenase, group 4, EchC subunit, putative; Identified by similarity to GP:3005969.
 
 0.997
DET0861
Hydrogenase, EchB subunit, putative; Identified by similarity to GP:3005968.
 
 
 0.971
DET0868
Hydrogenase, EchF subunit, putative; Identified by similarity to GP:3005972.
 
 
 0.953
nuoB
Proton-translocating NADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
     0.951
DET0860
Hydrogenase, EchA subunit, putative; Identified by similarity to GP:3005967.
 
   
 0.929
DET1570
Hydrogenase, group 4, HycG subunit, putative; Identified by similarity to SP:P77668.
 
 
 0.925
DET0866
Hydrogenase subunit, putative; Identified by similarity to SP:P76440.
  
 
 0.836
DET0864
Hydrogenase subunit HymB, putative; Identified by similarity to GP:14250934.
       0.786
DET0865
Hydrogenase subunit HymC, putative; Identified by similarity to GP:1032477.
       0.773
DET0863
Hydrogenase subunit HymA, putative; Identified by similarity to GP:14250933.
     
 0.742
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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