Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DET1037Serine protease, DegP/HtrA family; Identified by similarity to SP:O34358; similarity to SP:P09376. (373 aa)    
Predicted Functional Partners:
DET1036
Serine protease, DegP/HtrA family; Identified by similarity to SP:P09376.
 
  
 
0.977
DET1285
Serine protease, DegP/HtrA family; Identified by similarity to SP:O34358.
  
  
 
0.921
DET1513
ATPase, AAA family protein; Belongs to the AAA ATPase family.
    
 0.797
DET0600
Soluble hydrogenase, tritium exchange subunit; Identified by similarity to SP:P16421.
     
  0.569
trpB-2
Pyridoxal-phosphate dependent TrpB-like enzyme; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
       0.497
DET0521
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01OI0672.
    
  0.492
DET0522
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01ML1916.
    
  0.492
ilvB
Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF02776; match to protein family HMM TIGR00118.
     
  0.476
DET1321
Acetyltransferase, GNAT family; Identified by similarity to GP:29897287.
     
  0.476
DET0533
HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM TIGR01549.
   
 
  0.475
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
Server load: low (10%) [HD]