STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1094HNH endonuclease domain protein. (115 aa)    
Predicted Functional Partners:
DET1095
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.796
DET1091
Virulence-related protein; Identified by similarity to GP:3482866.
 
    0.782
DET1093
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.780
DET0065
Virulence-related protein; Identified by similarity to GP:3482866.
 
    0.651
DET1088
Terminase, large subunit, putative.
 
  
 0.651
DET0070
Hypothetical protein; Identified by Glimmer2; putative.
 
     0.634
DET1092
DNA methylase.
  
  
 0.611
DET1089
Virulence-related protein; Identified by similarity to GP:3482867.
 
     0.541
DET1090
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.529
purL
Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...]
   
    0.528
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.