Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DET1100DNA-dependent DNA polymerase, family A. (662 aa)    
Predicted Functional Partners:
DET1101
Conserved hypothetical protein; Identified by similarity to GP:18920552.
 
     0.866
DET1102
Conserved hypothetical protein; Identified by similarity to OMNI:EF0319.
 
     0.866
DET1097
Conserved hypothetical protein; Identified by similarity to OMNI:EF0329.
 
     0.783
DET0071
SNF2 family helicase, putative.
  
 
   0.779
DET1096
SNF2 domain protein.
  
 
   0.779
DET1098
Virulence-associated protein E, putative; Identified by similarity to GP:563258; match to protein family HMM PF05272.
 
     0.774
DET1103
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.744
glyS
glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
    
  0.663
ssb
Single-strand binding protein; Identified by match to protein family HMM TIGR00621.
   
 0.659
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.507
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.