STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1109Helicase domain/SNF2 family domain protein; Identified by match to protein family HMM TIGR01612. (1075 aa)    
Predicted Functional Partners:
DET1110
Conserved hypothetical protein; Identified by similarity to GP:26111617.
 
     0.959
DET1112
Type III restriction-modification system, methylase subunit; Identified by similarity to SP:P40814.
 
     0.959
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.954
DET1114
Type III restriction-modification system, restriction endonuclease subunit; Identified by similarity to SP:P08764.
 
     0.954
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.951
polA
DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.935
DET0330
Identified by match to protein family HMM PF00850.
    
 0.903
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.892
DET0183
ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by similarity to SP:P25888; Belongs to the DEAD box helicase family.
  
 0.874
DET0160
DNA polymerase domain protein.
    
 0.865
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.