| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DET0850 | DET1061 | DET0850 | DET1061 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM0209. | Identified by similarity to OMNI:CT0598; match to protein family HMM PF07521. | 0.867 |
| DET0850 | lepB | DET0850 | DET1192 | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM0209. | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | 0.901 |
| DET1061 | DET0850 | DET1061 | DET0850 | Identified by similarity to OMNI:CT0598; match to protein family HMM PF07521. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM0209. | 0.867 |
| DET1061 | lepB | DET1061 | DET1192 | Identified by similarity to OMNI:CT0598; match to protein family HMM PF07521. | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | 0.740 |
| DET1194 | lepB | DET1194 | DET1192 | Conserved hypothetical protein; Identified by similarity to OMNI:TM0646. | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | 0.689 |
| DET1194 | pyrE | DET1194 | DET1193 | Conserved hypothetical protein; Identified by similarity to OMNI:TM0646. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.689 |
| atpE | lepB | DET0559 | DET1192 | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | 0.857 |
| atpE | ribD | DET0559 | DET1190 | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.410 |
| atpE | rpmD | DET0559 | DET0492 | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | Ribosomal protein L30; Identified by match to protein family HMM PF00327; match to protein family HMM TIGR01308. | 0.800 |
| lepA | lepB | DET0859 | DET1192 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | 0.712 |
| lepA | rpmD | DET0859 | DET0492 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Ribosomal protein L30; Identified by match to protein family HMM PF00327; match to protein family HMM TIGR01308. | 0.928 |
| lepA | topA | DET0859 | DET0717 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.487 |
| lepB | DET0850 | DET1192 | DET0850 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM0209. | 0.901 |
| lepB | DET1061 | DET1192 | DET1061 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | Identified by similarity to OMNI:CT0598; match to protein family HMM PF07521. | 0.740 |
| lepB | DET1194 | DET1192 | DET1194 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | Conserved hypothetical protein; Identified by similarity to OMNI:TM0646. | 0.689 |
| lepB | atpE | DET1192 | DET0559 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | ATP synthase F0, C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.857 |
| lepB | lepA | DET1192 | DET0859 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.712 |
| lepB | pyrE | DET1192 | DET1193 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.806 |
| lepB | ribD | DET1192 | DET1190 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.606 |
| lepB | rnhB | DET1192 | DET0780 | Signal peptidase I; Identified by similarity to SP:P72365; match to protein family HMM PF00461; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.661 |