STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1232Sensor histidine kinase. (448 aa)    
Predicted Functional Partners:
DET1233
DNA-binding response regulator.
   0.968
DET0135
DNA-binding response regulator; Identified by similarity to GB:BAA02453.1.
 
   0.944
DET1058
DNA-binding response regulator.
 
   0.891
DET0130
Response regulator; Identified by similarity to SP:P13792.
 
   0.888
DET1231
DNA-binding response regulator.
 
   0.875
DET1016
Sensory box sensor histidine kinase/response regulator; Identified by match to protein family HMM TIGR00229; match to protein family HMM TIGR01612.
 
 
0.867
DET0232
DNA-binding response regulator.
 
   0.860
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.859
DET0732
Mercuric reductase, putative; Identified by similarity to SP:P16171; match to protein family HMM PF02852.
    
 0.858
DET0177
DNA-binding response regulator.
 
   0.857
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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