STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1285Serine protease, DegP/HtrA family; Identified by similarity to SP:O34358. (394 aa)    
Predicted Functional Partners:
DET1513
ATPase, AAA family protein; Belongs to the AAA ATPase family.
    
 0.917
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
  0.797
DET0521
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01OI0672.
    
  0.791
DET0522
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01ML1916.
    
  0.791
DET1631
TPR domain protein; Identified by match to protein family HMM PF00515.
    
 0.769
DET0533
HAD-superfamily hydrolase, subfamily IA; Identified by match to protein family HMM TIGR01549.
   
 
  0.683
DET1286
Serine protease, DegP/HtrA family; Identified by similarity to SP:P09376; match to protein family HMM PF00089.
 
    
0.631
DET0736
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by similarity to SP:P37769.
    
 0.556
fabG
3-oxoacyl-acyl carrier protein reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.556
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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