close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1350DNA-binding response regulator, LuxR family; Identified by similarity to SP:P13800. (225 aa)    
Predicted Functional Partners:
DET0431
Sensory box sensor histidine kinase; Identified by match to protein family HMM TIGR00229.
 0.984
DET0662
Sensor histidine kinase.
  
  0.983
DET1560
Sensory box sensor histidine kinase; Identified by match to protein family HMM TIGR00229.
 
 
 0.853
DET1064
Sensory box sensor histidine kinase; Identified by similarity to OMNI:NTL02MA1586; match to protein family HMM TIGR00229.
  
   0.840
DET1530
Sensor histidine kinase.
  
   0.817
DET1349
DNA-binding protein, excisionase family; Identified by match to protein family HMM TIGR01764.
       0.705
gspE
Type II secretion system protein GspE; Identified by similarity to GP:4139237; match to protein family HMM PF05157.
       0.517
DET1352
Pilin biogenesis protein, putative; Identified by similarity to SP:P45793.
       0.510
DET1353
Type II secretion system protein, GspI/GspJ family; Identified by similarity to SP:P15749.
  
    0.505
DET1354
Type II secretion system protein, putative; Identified by similarity to OMNI:NTL01XA0698.
  
    0.505
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.