STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (119 aa)    
Predicted Functional Partners:
hypB
Hydrogenase accessory protein HypB; Identified by similarity to SP:Q43949; match to protein family HMM PF01495; match to protein family HMM TIGR00073.
 
 
 0.991
hypD
Hydrogenase expression/formation protein HypD; Identified by similarity to SP:P24192; match to protein family HMM PF01924; match to protein family HMM TIGR00075.
 
  
 0.915
DET0110
[Ni/Fe] hydrogenase, group 1, large subunit, putative; Identified by similarity to SP:P21852; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.908
hypF
[NiFe] hydrogenase maturation protein HypF; Identified by similarity to SP:O07451; match to protein family HMM TIGR00143.
 
   
 0.907
hypC
Hydrogenase assembly chaperone HypC/HupF; Identified by similarity to GP:15430693; match to protein family HMM TIGR00074.
  
  
 0.889
hypE
Hydrogenase expression/formation protein HypE; Identified by similarity to SP:P40595.
 
  
 0.886
DET0104
Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.821
DET1571
Hydrogenase, group 4, HycE subunit, putative; Identified by similarity to SP:P77329; match to protein family HMM PF00346.
  
 
 0.760
DET1133
Iron-sulfur cluster-binding protein.
  
  
 0.566
DET0111
[Ni/Fe] hydrogenase, group 1, small subunit, putative; Identified by similarity to SP:P12943; match to protein family HMM PF01058; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409.
 
  
 0.550
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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