DET1472 protein (Dehalococcoides mccartyi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DET1472

NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643. (1834 aa)

Predicted Functional Partners:

trx-1

0.548

trx-2

0.548

guaA

0.490

DET1070

0.471

DET1148

0.438

DET1473

0.436

DET1621

0.435

nnrE

0.425

sod

0.415

Your Current Organism:

Dehalococcoides mccartyi

NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DET1070	DET1472	DET1070	DET1472	Endolysin, putative; Identified by match to protein family HMM PF01183.	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	0.471
DET1070	guaA	DET1070	DET0836	Endolysin, putative; Identified by match to protein family HMM PF01183.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.528
DET1070	nnrE	DET1070	DET0427	Endolysin, putative; Identified by match to protein family HMM PF01183.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.504
DET1148	DET1472	DET1148	DET1472	Nitrogenase cofactor biosynthesis protein NifB, putative.	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	0.438
DET1472	DET1070	DET1472	DET1070	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Endolysin, putative; Identified by match to protein family HMM PF01183.	0.471
DET1472	DET1148	DET1472	DET1148	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Nitrogenase cofactor biosynthesis protein NifB, putative.	0.438
DET1472	DET1473	DET1472	DET1473	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Hypothetical protein; Identified by Glimmer2; putative.	0.436
DET1472	DET1621	DET1472	DET1621	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Hypothetical protein; Identified by Glimmer2; putative.	0.435
DET1472	guaA	DET1472	DET0836	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.490
DET1472	nnrE	DET1472	DET0427	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	0.425
DET1472	sod	DET1472	DET0956	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Superoxide dismutase; Identified by similarity to SP:Q03300; match to protein family HMM PF02777.	0.415
DET1472	trx-1	DET1472	DET0661	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Thioredoxin; Identified by match to protein family HMM TIGR01068; Belongs to the thioredoxin family.	0.548
DET1472	trx-2	DET1472	DET0695	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	Thioredoxin; Identified by similarity to SP:P06544; match to protein family HMM PF00085; match to protein family HMM TIGR01068.	0.548
DET1473	DET1472	DET1473	DET1472	Hypothetical protein; Identified by Glimmer2; putative.	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	0.436
DET1621	DET1472	DET1621	DET1472	Hypothetical protein; Identified by Glimmer2; putative.	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	0.435
guaA	DET1070	DET0836	DET1070	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Endolysin, putative; Identified by match to protein family HMM PF01183.	0.528
guaA	DET1472	DET0836	DET1472	GMP synthase; Catalyzes the synthesis of GMP from XMP.	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	0.490
guaA	sod	DET0836	DET0956	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Superoxide dismutase; Identified by similarity to SP:Q03300; match to protein family HMM PF02777.	0.441
nnrE	DET1070	DET0427	DET1070	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	Endolysin, putative; Identified by match to protein family HMM PF01183.	0.504
nnrE	DET1472	DET0427	DET1472	Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]	NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643.	0.425

page 1 of 2

Server load: low (10%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Textmining

Co-expression

Databases

Fusion

© STRING Consortium 2026

Credits

Access

Info

About