STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1472NHL/RHS/YD repeat protein; Identified by match to protein family HMM PF01436; match to protein family HMM TIGR01612; match to protein family HMM TIGR01643. (1834 aa)    
Predicted Functional Partners:
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
    0.486
DET1621
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.457
DET1070
Endolysin, putative; Identified by match to protein family HMM PF01183.
     
 0.449
DET1336
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.443
DET1473
Hypothetical protein; Identified by Glimmer2; putative.
       0.436
nnrE
Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]
       0.418
DET1016
Sensory box sensor histidine kinase/response regulator; Identified by match to protein family HMM TIGR00229; match to protein family HMM TIGR01612.
     
 0.412
DET1348
RNA polymerase sigma-70 factor, ECF subfamily; Identified by similarity to SP:Q45585; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.411
DET0169
RNA polymerase sigma factor SigW, putative; Identified by similarity to SP:Q45585; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.402
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.