STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DET1502Major facilitator family protein; Identified by similarity to OMNI:NTL01MM3272. (465 aa)    
Predicted Functional Partners:
DET1504
Ferrous iron transport protein A, putative; Identified by similarity to OMNI:NTL01TT0221.
 
     0.706
DET1503
Ferrous iron transport protein B, putative; Identified by similarity to SP:P33650; match to protein family HMM TIGR00231.
   
 
 0.647
DET1505
Transcriptional regulator, Fur family; Identified by similarity to GP:22776586; Belongs to the Fur family.
       0.521
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.520
DET0961
Conserved hypothetical protein; Identified by similarity to OMNI:NTL01MM1085; match to protein family HMM PF01995.
  
     0.454
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.415
DET0325
Identified by match to protein family HMM PF01734.
 
      0.413
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.