STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DET1503Ferrous iron transport protein B, putative; Identified by similarity to SP:P33650; match to protein family HMM TIGR00231. (576 aa)    
Predicted Functional Partners:
DET1504
Ferrous iron transport protein A, putative; Identified by similarity to OMNI:NTL01TT0221.
 
  
 0.968
DET0097
Iron dependent repressor, putative; Identified by match to protein family HMM PF02742.
 
  
 0.869
DET1505
Transcriptional regulator, Fur family; Identified by similarity to GP:22776586; Belongs to the Fur family.
     
 0.659
DET0096
Identified by match to protein family HMM PF04023.
  
  
 0.642
DET1502
Major facilitator family protein; Identified by similarity to OMNI:NTL01MM3272.
   
 
 0.642
DET0953
Copper-translocating P-type ATPase; Identified by similarity to SP:P37279; match to protein family HMM PF00403; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525.
  
 
 0.567
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
     
 0.486
DET0651
ABC-type cobalamin/Fe3+-siderophores transport systems, permease component; Identified by similarity to PIR:S54438; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
    
 
 0.436
DET0685
ABC-type cobalamin/Fe3+-siderophores transport systems, permease component; Identified by similarity to PIR:S54438.
    
 
 0.436
DET1632
Identified by match to protein family HMM PF01106.
     
 0.434
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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