Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
DET1581Antioxidant, AhpC/TSA family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. (213 aa)    
Predicted Functional Partners:
DET1007
Identified by match to protein family HMM TIGR00412.
  
 0.962
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM TIGR01292.
  
 
 0.888
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.846
DET1582
Conserved domain protein; Identified by similarity to OMNI:AF1697.
       0.781
sod
Superoxide dismutase; Identified by similarity to SP:Q03300; match to protein family HMM PF02777.
  
  
 0.603
DET0955
Bacterioferritin domain protein; Identified by similarity to SP:P49944; Belongs to the Dps family.
  
  
 0.570
DET0153
Conserved domain protein; Identified by similarity to GP:560723.
  
  
 0.546
hflX
GTP-binding protein, putative; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
 
      0.544
DET0020
Transcriptional regulator, Fur family; Identified by similarity to OMNI:NTL01TT1159; Belongs to the Fur family.
  
  
 0.535
DET0630
Transcriptional regulator, Fur family; Belongs to the Fur family.
  
  
 0.535
Your Current Organism:
Dehalococcoides mccartyi
NCBI taxonomy Id: 243164
Other names: D. mccartyi 195, Dehalococcoides ethenogenes 195, Dehalococcoides mccartyi 195, Dehalococcoides mccartyi str. 195, Dehalococcoides mccartyi strain 195
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