node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR_2411 | dnaE | DR_2411 | DR_0507 | Hypothetical protein; Identified by Glimmer2; putative. | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative DNA synthesis in bacteria as well as the bulk of DNA synthesis/repair after ionizing radiation (IR). The alpha chain is the catalytic subunit. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synt [...] | 0.797 |
DR_2411 | dnaX | DR_2411 | DR_2410 | Hypothetical protein; Identified by Glimmer2; putative. | DNA polymerase III, tau/gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.964 |
DR_2411 | ssb | DR_2411 | DR_0099 | Hypothetical protein; Identified by Glimmer2; putative. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism (By similarity). Essential for ionizing radiation resistance. Stimulates the 5'-3' DNA helicase activity of RecD-like helicase. Stimulates RecA protein- promoted DNA three-strand exchange reactions in vitro with both D.radiodurans and E.coli-derived RecA. Complements an ssb deletion in E.coli, but does not complement a ddrb disruption in D.radiodurans. | 0.784 |
dnaE | DR_2411 | DR_0507 | DR_2411 | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative DNA synthesis in bacteria as well as the bulk of DNA synthesis/repair after ionizing radiation (IR). The alpha chain is the catalytic subunit. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synt [...] | Hypothetical protein; Identified by Glimmer2; putative. | 0.797 |
dnaE | dnaX | DR_0507 | DR_2410 | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative DNA synthesis in bacteria as well as the bulk of DNA synthesis/repair after ionizing radiation (IR). The alpha chain is the catalytic subunit. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synt [...] | DNA polymerase III, tau/gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.982 |
dnaE | ssb | DR_0507 | DR_0099 | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative DNA synthesis in bacteria as well as the bulk of DNA synthesis/repair after ionizing radiation (IR). The alpha chain is the catalytic subunit. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synt [...] | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism (By similarity). Essential for ionizing radiation resistance. Stimulates the 5'-3' DNA helicase activity of RecD-like helicase. Stimulates RecA protein- promoted DNA three-strand exchange reactions in vitro with both D.radiodurans and E.coli-derived RecA. Complements an ssb deletion in E.coli, but does not complement a ddrb disruption in D.radiodurans. | 0.947 |
dnaE | topA | DR_0507 | DR_1374 | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative DNA synthesis in bacteria as well as the bulk of DNA synthesis/repair after ionizing radiation (IR). The alpha chain is the catalytic subunit. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synt [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.561 |
dnaX | DR_2411 | DR_2410 | DR_2411 | DNA polymerase III, tau/gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Hypothetical protein; Identified by Glimmer2; putative. | 0.964 |
dnaX | dnaE | DR_2410 | DR_0507 | DNA polymerase III, tau/gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, alpha subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative DNA synthesis in bacteria as well as the bulk of DNA synthesis/repair after ionizing radiation (IR). The alpha chain is the catalytic subunit. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synt [...] | 0.982 |
dnaX | ssb | DR_2410 | DR_0099 | DNA polymerase III, tau/gamma subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism (By similarity). Essential for ionizing radiation resistance. Stimulates the 5'-3' DNA helicase activity of RecD-like helicase. Stimulates RecA protein- promoted DNA three-strand exchange reactions in vitro with both D.radiodurans and E.coli-derived RecA. Complements an ssb deletion in E.coli, but does not complement a ddrb disruption in D.radiodurans. | 0.854 |
rplI | rplJ | DR_0102 | DR_2044 | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | Ribosomal protein L10; Similar to SP:P29394 GB:X72695 GB:Z11839 PID:425256 PID:581803 percent identity: 52.10; identified by sequence similarity; putative. | 0.998 |
rplI | rplU | DR_0102 | DR_0086 | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | Ribosomal protein L21; Binds directly to 23S rRNA, probably serving to organize its structure; Belongs to the bacterial ribosomal protein bL21 family. | 0.999 |
rplI | rpsF | DR_0102 | DR_0098 | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.999 |
rplI | rpsG | DR_0102 | DR_0306 | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.993 |
rplI | rpsJ | DR_0102 | DR_0310 | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.993 |
rplI | ssb | DR_0102 | DR_0099 | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism (By similarity). Essential for ionizing radiation resistance. Stimulates the 5'-3' DNA helicase activity of RecD-like helicase. Stimulates RecA protein- promoted DNA three-strand exchange reactions in vitro with both D.radiodurans and E.coli-derived RecA. Complements an ssb deletion in E.coli, but does not complement a ddrb disruption in D.radiodurans. | 0.730 |
rplJ | rplI | DR_2044 | DR_0102 | Ribosomal protein L10; Similar to SP:P29394 GB:X72695 GB:Z11839 PID:425256 PID:581803 percent identity: 52.10; identified by sequence similarity; putative. | Ribosomal protein L9; Binds to the 23S rRNA and protein L31; Belongs to the bacterial ribosomal protein bL9 family. | 0.998 |
rplJ | rplU | DR_2044 | DR_0086 | Ribosomal protein L10; Similar to SP:P29394 GB:X72695 GB:Z11839 PID:425256 PID:581803 percent identity: 52.10; identified by sequence similarity; putative. | Ribosomal protein L21; Binds directly to 23S rRNA, probably serving to organize its structure; Belongs to the bacterial ribosomal protein bL21 family. | 0.998 |
rplJ | rpsF | DR_2044 | DR_0098 | Ribosomal protein L10; Similar to SP:P29394 GB:X72695 GB:Z11839 PID:425256 PID:581803 percent identity: 52.10; identified by sequence similarity; putative. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.998 |
rplJ | rpsG | DR_2044 | DR_0306 | Ribosomal protein L10; Similar to SP:P29394 GB:X72695 GB:Z11839 PID:425256 PID:581803 percent identity: 52.10; identified by sequence similarity; putative. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |