STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
norMConserved hypothetical protein; Multidrug efflux pump; Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. (451 aa)    
Predicted Functional Partners:
mscL
Large conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.790
DR_0792
Conserved hypothetical protein; Similar to GB:U00096 SP:P76352 PID:2367126 percent identity: 51.47; identified by sequence similarity; putative.
  
     0.747
DR_0106
Hypothetical protein; Identified by Glimmer2; putative.
       0.658
DR_0862
Phytoene synthase; Similar to SP:P37270 PID:575608 percent identity: 60.07; identified by sequence similarity; putative.
   
 
 0.628
DR_1343
Glyceraldehyde 3-phosphate dehydrogenase; Similar to SP:P00361 GB:X16595 PID:48121 percent identity: 81.52; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
  
 0.550
RpsA
Ribosomal protein S1, putative; Similar to SP:P14129 GB:X07528 PID:46339 percent identity: 65.09; identified by sequence similarity; putative.
  
    0.524
DR_0105
Hypothetical protein; Identified by Glimmer2; putative.
       0.472
DR_2367
Glutathione-regulated potassium-efflux system protein KefB, putative; Similar to GB:AE000666 percent identity: 56.42; identified by sequence similarity; putative; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
  
  
 0.454
DR_1659
Similar to GB:M84574 SP:P27237 PID:154214 percent identity: 60.62; identified by sequence similarity; putative.
 
   
 0.421
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.416
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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