STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR_0196Anthranilate synthase component I; Similar to GB:AE000666 percent identity: 50.00; identified by sequence similarity; putative. (638 aa)    
Predicted Functional Partners:
trpC
Indole-3-glycerol phosphate synthase; Similar to PID:2113895 GB:AL123456 percent identity: 57.65; identified by sequence similarity; putative; Belongs to the TrpC family.
 
 0.999
trpD
Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 0.999
trpF
Phosphoribosylanthranilate isomerase; Similar to PID:1054860 SP:Q56320 GB:AE000512 percent identity: 57.92; identified by sequence similarity; putative; Belongs to the TrpF family.
 
  
 0.998
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.998
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.998
DR_0195
Hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.949
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
 
0.871
DR_1766
Anthranilate synthase component II; Similar to GB:AE000657 percent identity: 76.17; identified by sequence similarity; putative.
 
 
0.847
DR_0168
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
  
 0.817
DR_1001
Phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; Similar to GB:X65945 SP:P39912 PID:39813 PID:2293220 GB:AL009126 percent identity: 73.86; identified by sequence similarity; putative.
 
  
 0.792
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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