Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DR_0728Fructokinase; Similar to PID:2293420 percent identity: 55.36; identified by sequence similarity; putative. (303 aa)    
Predicted Functional Partners:
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 0.919
DR_A0154
Glucosamine--fructose-6-phosphate aminotransferase-related protein; Similar to PID:1184044 SP:Q56213 percent identity: 52.76; identified by sequence similarity; putative.
  
 
 0.918
pgi
Glucose-6-phosphate isomerase; Similar to GP:3334790 percent identity: 79.44; identified by sequence similarity; putative.
  
 
 0.914
DR_A0048
Mannose-6-phosphate isomerase, putative; Similar to GB:D16594 PID:451216 SP:Q59935 percent identity: 59.61; identified by sequence similarity; putative.
    
 0.908
DR_0723
Glycosyl hydrolase, family 13; Similar to GB:D13178 SP:Q08751 PID:398125 percent identity: 53.32; identified by sequence similarity; putative.
   
 0.905
DR_1375
Glycosyl hydrolase, family 13; Similar to SP:P07192 PID:7779 percent identity: 57.84; identified by sequence similarity; putative.
   
 0.905
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
    
 0.903
DR_1525
Carbohydrate kinase, PfkB family; Similar to GB:L10328 SP:P05054 GB:M13169 PID:147516 PID:290602 percent identity: 45.17; identified by sequence similarity; putative; Belongs to the carbohydrate kinase PfkB family.
  
     0.731
DR_0729
Hydrolase, CbbY/CbbZ/GpH/YieH family; Similar to GP:1518395 percent identity: 49.05; identified by sequence similarity; putative.
 
   
 0.620
DR_1884
Transcriptional regulator; Similar to GB:AL009126 percent identity: 50.91; identified by sequence similarity; putative.
 
  
 0.595
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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