STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DR_1111Transcriptional regulator, MerR family; Similar to GB:AL009126 percent identity: 52.63; identified by sequence similarity; putative. (137 aa)    
Predicted Functional Partners:
DR_1112
Hypothetical protein; Identified by Glimmer2; putative.
       0.559
DR_1113
Hypothetical protein; Identified by Glimmer2; putative.
       0.559
DR_2519
Transcriptional regulator, MerR family; Similar to GP:2808790 percent identity: 48.04; identified by sequence similarity; putative.
  
     0.525
DR_1114
Heat shock protein, HSP20 family; Similar to PID:818211 SP:Q53595 percent identity: 56.43; identified by sequence similarity; putative; Belongs to the small heat shock protein (HSP20) family.
  
    0.474
DR_0451
Glutamine synthase; Similar to SP:P10656 PID:144818 percent identity: 73.52; identified by sequence similarity; putative; Belongs to the glutamine synthetase family.
  
 
 0.451
DR_2448
Transcriptional regulator, MerR family; Similar to GB:L25604 SP:P39075 PID:409288 PID:1303945 percent identity: 49.22; identified by sequence similarity; putative.
  
     0.444
DR_2482
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.442
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
  
 
 0.433
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.425
DR_1108
Hypothetical protein; Identified by Glimmer2; putative.
       0.423
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.