Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
DR_1200Hypothetical protein; Identified by Glimmer2; putative. (335 aa)    
Predicted Functional Partners:
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
  
 0.776
dnaK
dnaK protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.744
DR_0833
Histone deacetylase/AcuC/AphA family protein; Similar to SP:P28606 PID:580726 PID:669044 PID:669045 percent identity: 59.38; identified by sequence similarity; putative.
  
 0.729
DR_1185
S-layer-like array-related protein; Similar to PID:993026 percent identity: 58.12; identified by sequence similarity; putative.
  
     0.725
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.718
DR_0647
Cell division cycle protein 48-related protein; Similar to SP:P54774 PID:862480 percent identity: 62.63; identified by sequence similarity; putative; Belongs to the AAA ATPase family.
   
 0.716
DR_A0287
Hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.714
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.709
DR_1115
S-layer-like array-related protein; Similar to PID:993026 percent identity: 63.68; identified by sequence similarity; putative.
  
     0.699
DR_0975
MutT/nudix family protein; Similar to GB:L42023 SP:P44932 PID:1006021 PID:1221014 PID:1205157 percent identity: 79.31; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
  
     0.689
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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