STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpmIRibosomal protein L35; Binds the 23S rRNA; Belongs to the bacterial ribosomal protein bL35 family. (66 aa)    
Predicted Functional Partners:
rplT
Ribosomal protein L20; Binds directly to 23S rRNA, probably serving to organize its structure; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.999
rplK
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.999
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit (By similarity). Binds to the 23S rRNA.
  
 
 0.998
rplV
Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
 
 0.998
rpmC
Ribosomal protein L29; Binds the 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.998
rplO
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
   
 
 0.998
rplQ
Ribosomal protein L17; Binds to the 23S rRNA; Belongs to the bacterial ribosomal protein bL17 family.
   
 
 0.998
rpmF
Ribosomal protein L32; Forms a cluster with L17 and L22, and with L22, a pair of 'tweezers' that hold together all the domains of the 23S rRNA. Interacts with the antibiotic troleandomycin which blocks the peptide exit tunnel.
  
 
 0.998
rpmB
Ribosomal protein L28; Similar to GB:AE000783 percent identity: 64.86; identified by sequence similarity; putative.
  
 
 0.998
rplU
Ribosomal protein L21; Binds directly to 23S rRNA, probably serving to organize its structure; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.997
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.