Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DR_2199ATP-dependent DNA helicase RecG-related protein; Similar to SP:O50224 percent identity: 49.24; identified by sequence similarity; putative. (596 aa)    
Predicted Functional Partners:
recG
DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
    
 0.903
DR_2197
ABC transporter, permease protein, CysTW family; Similar to PID:1054577 GB:U00096 SP:Q47539 PID:1384060 PID:1657562 percent identity: 50.78; identified by sequence similarity; putative.
       0.479
DR_2198
ABC transporter, ATP-binding protein; Similar to SP:P38046 PID:397157 PID:48972 percent identity: 66.67; identified by sequence similarity; putative.
       0.479
DR_0975
MutT/nudix family protein; Similar to GB:L42023 SP:P44932 PID:1006021 PID:1221014 PID:1205157 percent identity: 79.31; identified by sequence similarity; putative; Belongs to the Nudix hydrolase family.
 
    0.474
DR_1013
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.469
lexA
lexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
     
 0.404
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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