Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DR_2280Uracil permease; Similar to GB:X76083 SP:P41006 PID:431231 percent identity: 70.23; identified by sequence similarity; putative. (496 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Similar to PID:1684759 percent identity: 73.09; identified by sequence similarity; putative; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.839
pyrR
Pyrimidine operon regulatory protein PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
  
  
 0.729
pyrF
Orotidine 5`-phosphate decarboxylase; Similar to PID:1754505 percent identity: 63.03; identified by sequence similarity; putative; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.680
carB
Carbamoyl-phosphate synthase, large subunit; Similar to PID:1872144 percent identity: 80.36; identified by sequence similarity; putative.
  
  
 0.664
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.653
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.629
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 0.625
DR_A0183
Conserved hypothetical protein; Similar to GB:L77117 SP:Q57772 PID:1591045 percent identity: 71.53; identified by sequence similarity; putative.
 
  
 0.583
DR_2281
Hypothetical protein; Identified by Glimmer2; putative.
       0.564
DR_2282
Conserved hypothetical protein; Similar to SP:P45465 PID:606088 GB:U00096 PID:1789538 percent identity: 56.57; identified by sequence similarity; putative; Belongs to the UPF0102 family.
       0.564
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
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