node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DR_1775 | cinA | DR_1775 | DR_2338 | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | 0.465 |
DR_1775 | polA | DR_1775 | DR_1707 | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | DNA-directed DNA polymerase; A DNA polymerase, required for DNA repair after DNA damage induced by ionizing radiation (IR); this is not the major DNA polymerase. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synthesis requires both RecA and RadA, Pol III initiates DNA synthesis while both Pol I and Pol III are require [...] | 0.761 |
DR_1775 | radA | DR_1775 | DR_1105 | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | DNA repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. Belongs to the RecA family. RadA subfamily. | 0.706 |
DR_1775 | recA | DR_1775 | DR_2340 | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity). Probably involved in base excision repair ; Belongs to the RecA family. | 0.912 |
DR_1775 | recN | DR_1775 | DR_1477 | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | DNA repair protein; May be involved in recombinational repair of damaged DNA. Belongs to the RecN family. | 0.488 |
DR_1775 | recR | DR_1775 | DR_0198 | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | recR protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.663 |
DR_2339 | cinA | DR_2339 | DR_2338 | 2`-5` RNA ligase, putative; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | 0.963 |
DR_2339 | recA | DR_2339 | DR_2340 | 2`-5` RNA ligase, putative; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity). Probably involved in base excision repair ; Belongs to the RecA family. | 0.884 |
DR_A0074 | polA | DR_A0074 | DR_1707 | Hypothetical protein; Identified by Glimmer2; putative. | DNA-directed DNA polymerase; A DNA polymerase, required for DNA repair after DNA damage induced by ionizing radiation (IR); this is not the major DNA polymerase. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synthesis requires both RecA and RadA, Pol III initiates DNA synthesis while both Pol I and Pol III are require [...] | 0.455 |
DR_A0074 | recA | DR_A0074 | DR_2340 | Hypothetical protein; Identified by Glimmer2; putative. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity). Probably involved in base excision repair ; Belongs to the RecA family. | 0.913 |
DR_A0074 | recN | DR_A0074 | DR_1477 | Hypothetical protein; Identified by Glimmer2; putative. | DNA repair protein; May be involved in recombinational repair of damaged DNA. Belongs to the RecN family. | 0.523 |
cinA | DR_1775 | DR_2338 | DR_1775 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | DNA helicase II; Similar to GB:M87049 SP:P03018 GB:D00069 GB:X00225 GB:X00738 percent identity: 61.60; identified by sequence similarity; putative. | 0.465 |
cinA | DR_2339 | DR_2338 | DR_2339 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | 2`-5` RNA ligase, putative; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. | 0.963 |
cinA | lexA | DR_2338 | DR_A0344 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | lexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.594 |
cinA | polA | DR_2338 | DR_1707 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | DNA-directed DNA polymerase; A DNA polymerase, required for DNA repair after DNA damage induced by ionizing radiation (IR); this is not the major DNA polymerase. Following severe irradiation (7 kGy of gamma irradiation) genomic DNA is fragmented. DNA is progressively degraded for the first 1.5 hours after IR, in a step promoted by RecA and counterbalanced by DNA Pol I and Pol III, followed by massive DNA synthesis and genome reassembly in the next hour. Optimal priming of DNA synthesis requires both RecA and RadA, Pol III initiates DNA synthesis while both Pol I and Pol III are require [...] | 0.747 |
cinA | recA | DR_2338 | DR_2340 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity). Probably involved in base excision repair ; Belongs to the RecA family. | 0.973 |
cinA | recN | DR_2338 | DR_1477 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | DNA repair protein; May be involved in recombinational repair of damaged DNA. Belongs to the RecN family. | 0.446 |
cinA | recR | DR_2338 | DR_0198 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | recR protein; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.639 |
cinA | recX | DR_2338 | DR_1310 | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | Regulatory protein RecX, putative; Modulates RecA activity; Belongs to the RecX family. | 0.669 |
lexA | cinA | DR_A0344 | DR_2338 | lexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | cinA protein; Similar to PID:2251087 percent identity: 100.00; identified by sequence similarity; putative; Belongs to the CinA family. | 0.594 |