STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (304 aa)    
Predicted Functional Partners:
DR_2635
Pyruvate kinase; Similar to PID:598097 SP:Q46078 percent identity: 63.38; identified by sequence similarity; putative; Belongs to the pyruvate kinase family.
  
 0.990
DR_2583
Malate oxidoreductase; Similar to SP:P45868 PID:853772 GB:AL009126 percent identity: 65.68; identified by sequence similarity; putative.
  
 0.935
DR_A0276
Malate oxidoreductase; Similar to GB:AL009126 percent identity: 67.66; identified by sequence similarity; putative.
  
 0.932
DR_0030
2-oxo acid dehydrogenase, E1 component, beta subunit; Similar to GB:M97391 SP:P37941 PID:142612 PID:1303943 GB:AL009126 percent identity: 71.16; identified by sequence similarity; putative.
  
 0.926
DR_0623
Aspartate aminotransferase; Similar to PID:1255699 percent identity: 75.92; identified by sequence similarity; putative.
  
 0.919
DR_0029
2-oxo acid dehydrogenase, E1 component, alpha subunit; Similar to SP:P11960 PID:203121 percent identity: 55.26; identified by sequence similarity; putative.
  
 
 0.914
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.914
AceE
Pyruvate dehydrogenase complex, E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.911
DR_1026
Oxidoreductase; Similar to PID:602029 percent identity: 59.86; identified by sequence similarity; putative.
   
 
 0.907
DR_0217
Thiosulfate sulfurtransferase; Similar to GB:M29612 SP:P16385 PID:152687 percent identity: 73.72; identified by sequence similarity; putative.
   
 
 0.906
Your Current Organism:
Deinococcus radiodurans
NCBI taxonomy Id: 243230
Other names: D. radiodurans R1, Deinococcus radiodurans R1, Deinococcus radiodurans str. R1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.