STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSU0019Pentapeptide repeat domain protein. (292 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.823
GSU2248
Hypothetical protein.
  
  
 0.618
GSU0869
Protein of unknown function, LysM, LysM and NLPC_P60 domain-containing; Domains: LysM, LysM, NLPC_P60.
   
 
 0.546
GSU1010
Lytic transglycosylase, SLT, LysM and LysM domain-containing; Domains: SLT, LysM, LysM.
   
 
 0.531
GSU3417
Dioxygenase, putative.
  
     0.527
GSU2610
LysM domain protein.
   
 
 0.525
GSU3276
LysM domain protein.
   
 
 0.525
pal
Peptidoglycan-binding outer membrane lipoprotein Pal, OmpA family; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.470
GSU0018
Helix-turn-helix transcriptional regulator with aminotransferase domain, GntR family.
  
    0.459
GSU3191
TPR domain protein.
 
  
 0.447
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.