Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
can-1Carbonic anhydrase, beta-family, clade B. (215 aa)    
Predicted Functional Partners:
GSU1442
Carbonic anhydrase, beta-family, clade C.
  
  
 
0.926
can-2
Carbonic anhydrase, beta-family, clade B; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
  
 
0.918
GSU0809
Carbonic anhydrase, beta-family, clade D.
     
  0.900
GSU0066
Peroxiredoxin-like 2 family protein, selenocysteine-containing.
  
    0.797
namA
NADPH-dependent enal/enone/nitroreductase, Oye family.
   
  
 0.738
fdhC
Bidirectional formate transporter, putative.
  
    0.704
GSU0069
Oxidoreductase, iron-sulfur cluster-binding subunit.
  
    0.626
GSU0068
Cytochrome c; 4 heme-binding sites.
  
    0.621
nifU
Nitrogen fixation iron-sulfur cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
  
 0.586
nifH
Nitrogenase iron protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family.
   
  
 0.584
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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