Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hdrFHeterodisulfide oxidoreductase, NAD(P)H oxidoreductase subunit F. (280 aa)    
Predicted Functional Partners:
hdrE
Heterodisulfide oxidoreductase, iron-sulfur cluster-binding subunit E.
  
 0.997
hdrD
Heterodisulfide oxidoreductase, iron-sulfur cluster-binding subunit D.
 
  
 0.966
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
 
 
 0.964
hdrG
Heterodisulfide oxidoreductase, iron-sulfur cluster-binding subunit G.
 
 
 0.962
hdrA
Heterodisulfide oxidoreductase, FAD-binding and iron-sulfur cluster-binding subunit A.
 
  
 0.962
hdrB
Heterodisulfide oxidoreductase, CCG domain pair-containing subunit B.
 
  
 0.954
hdrC
Heterodisulfide oxidoreductase, iron-sulfur cluster-binding subunit C.
 
  
 0.951
carB
Carbamyl-phosphate synthase, large subunit lipoprotein, glutamine-dependent; Belongs to the CarB family.
  
 
 0.819
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.814
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.813
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.