Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
GSU0474Sensor diguanylate cyclase/phosphodiesterase, PAS and PAS domain-containing; Domains: PAS, PAS, GGDEF, EAL. (792 aa)    
Predicted Functional Partners:
GSU1655
Response receiver sensor histidine kinase response regulator, PAS and GAF domain-containing; Domains: REC, PAS, GAF, HisKA, HATPase_c, REC.
  
 
 0.872
GSU1007
Sensor cyclic diguanylate phosphodiesterase, GAF and GAF domain-containing; Domains: GAF, GAF, HD-GYP.
 
 
 0.856
GSU0537
Sensor diguanylate cyclase/phosphodiesterase, PAS domain-containing; Domains: PAS, GGDEF, EAL.
 
 
0.833
GSU2511
Sensor diguanylate cyclase/phosphodiesterase, CHASE4 and PAS domain-containing; Domains: CHASE4, PAS, GGDEF, EAL.
 
 
0.826
GSU1870
Sensor diguanylate cyclase, GAF domain-containing; Domains: GAF, GGDEF.
 
 
 
0.813
GSU1037
Response receiver-modulated diguanylate cyclase/phosphodiesterase; Domains: REC, GGDEF, EAL.
 
 
0.809
GSU1555
Sensor histidine kinase response regulator, 5TM, PAS, PAS, GAF and PAS domain-containing; Domains: 5TM, PAS, PAS, GAF, PAS, HisKA, HATPase_c, REC.
  
 
 0.805
GSU1302
Sensor histidine kinase response regulator, HAMP domain-containing, putative heme-binding site; Domains: HAMP, HisKA, HATPase_c, REC.
  
 
 0.794
GSU2314
Sensor histidine kinase response regulator; Domains: DUF3365, PAS, PAS, HisKA, HATPase_c, REC, Hpt.
  
 
 0.773
GSU2575
Sensor histidine kinase response regulator, Hpt domain-containing; Domains: HisKA, HATPase_c, REC, Hpt.
 
 0.766
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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