Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppk-2Polyphosphate-dependent AMP kinase. (492 aa)    
Predicted Functional Partners:
ppk-1
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
 
   
 0.792
hemN
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
    0.629
GSU3127
Helix-turn-helix transcriptional regulator, AraC family.
   
    0.620
GSU3334
Lipoprotein cytochrome c, 1 heme-binding site.
   
    0.620
gppA-2
pppGpp 5'-phosphohydrolase and exopolyphosphatase, HD domain-containing.
 
  
 0.607
GSU2417
Hypothetical protein; mvhR.
   
    0.568
GSU0073
Outer membrane protein, putative.
   
    0.524
GSU0360
Peptidoglycan-binding outer membrane protein, OMP_b-brl and OmpA domain-containing; Domains: OMP_b-brl, OmpA.
   
    0.524
GSU0810
Peptidoglycan-binding outer membrane protein, OMP_b-brl, OmpA and OmpA domain-containing; Domains: OMP_b-brl, OmpA, OmpA.
   
    0.524
GSU0727
Lipoprotein, putative.
  
    0.475
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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