Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
ppsAPhosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)    
Predicted Functional Partners:
por
Pyruvate:ferredoxin/flavodoxin oxidoreductase.
    
 0.966
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.963
maeB
Malate oxidoreductase, NADP-dependent, phosphate acetyltransferase-like domain-containing.
  
 
 0.958
pckA
Phosphoenolpyruvate carboxykinase, GTP-dependent; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
     
 0.948
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.940
pdhB
Pyruvate dehydrogenase complex, E1 protein, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.939
korA
2-oxoglutarate:ferredoxin oxidoreductase, alpha subunit.
    
 0.937
korB
2-oxoglutarate:ferredoxin oxidoreductase, thiamin diphosphate-binding subunit.
    
 0.937
pdhA
Pyruvate dehydrogenase complex, E1 protein, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.937
ppdK
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
0.922
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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