Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSU0963Sigma-54-dependent transcriptional response regulator; Domains: REC, sigma54 interaction, HTH8. (464 aa)    
Predicted Functional Partners:
GSU0962
Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c.
 
   0.821
rpoN
RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.737
gnfL
Nitrogen fixation master sensor histidine kinase, PAS domain-containing; Domains: PAS, HisKA, HATPase_c.
 
 
 0.618
GSU0613
ResB-like family cytochrome c biogenesis protein.
      
 0.581
flhG
Flagellar biogenesis ATPase FlhG.
  
 
 0.503
GSU1990
Sensor histidine kinase, NtrB-related protein; Domains: HisKA, HATPase_c.
 
 
 0.485
macA
Cytochrome c peroxidase; 2 heme-binding sites.
      
 0.434
GSU3216
Sensor histidine kinase; Domains: HATPase_c.
 
   0.420
GSU0283
Sensor histidine kinase, GAF and GAF domain-containing, nonconserved putative heme-binding site; Domains: GAF, GAF, HisKA, HATPase_c.
 
 
 
 0.418
GSU1768
ParA family protein.
  
 
 0.411
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.