STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ycbLZinc-dependent hydrolase YcbL. (209 aa)    
Predicted Functional Partners:
GSU2309
Metal-dependent hydrolase, beta-lactamase superfamily.
 
0.941
yhaM
3'-to-5' exonuclease YhaM.
  
    0.894
GSU0794
FAD-dependent pyridine nucleotide-disulfide oxidoreductase family protein, rhodanese homology domain-containing.
  
 0.805
GSU1121
FAD-dependent oxidoreductase, putative.
  
    0.751
coaBC
Phosphopantothenylcysteine decarboxylase and phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
    0.731
GSU1120
Response receiver; Domains: REC.
  
    0.671
purSL
Phosphoribosylformylglycinamidine synthase, PurS and PurL domains; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and i [...]
  
    0.642
GSU0008
Response receiver sensor histidine kinase, PAS domain-containing; Domains: REC, PAS, HisKA, HATPase_c.
  
  
 0.640
GSU0843
Rubredoxin reductase.
   
 0.602
ycbK
Protein of unknown function YcbK.
  
    0.590
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.