STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lpdA-4Dihydrolipoamide dehydrogenase. (505 aa)    
Predicted Functional Partners:
GSU3019
Dehydrogenase, E1 protein, alpha and beta subunits.
  
 0.996
GSU1314
Membrane protein, putative.
    0.985
aceF
Pyruvate dehydrogenase complex, E2 protein, dihydrolipoamide acetyltransferase.
 0.963
bkdF
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex; Branched-chain 2-oxoacid dehydrogenase complex, E2 protein, dihydrolipoamide acyltransferase, putative.
 0.940
sucB
2-oxoglutarate dehydrogenase, E2 protein, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.931
pdhB
Pyruvate dehydrogenase complex, E1 protein, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.918
bkdB
Branched-chain 2-oxoacid dehydrogenase complex, E1 protein, beta subunit, putative.
 
 0.918
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
      0.895
sucA
2-oxoglutarate dehydrogenase, E1 protein.
  
 0.885
pdhA
Pyruvate dehydrogenase complex, E1 protein, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 
 0.846
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.