STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilSSensor histidine kinase PilS, PAS domain-containing; Domains: PAS, HisKA, HATPase_c. (550 aa)    
Predicted Functional Partners:
pilR
Sigma-54-dependent transcriptional response regulator PilR; Domains: REC, sigma54 interaction, HTH8.
 
 0.994
rpoN
RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
    
 0.915
pilC
Type IV pilus inner membrane protein PilC.
  
  
 0.911
pilT-4
Twitching motility pilus retraction protein.
  
  
 0.869
GSU2046
Response regulator; Domains: REC.
  
 
 
 0.810
cheY40H-2
Response receiver CheY associated with MCPs of class 40H.
 
 
 
 0.768
cheY40H-1
Response receiver CheY associated with MCPs of class 40H.
  
 
 0.766
GSU1117
Response regulator, putative; Domains: REC.
 
 
 0.746
GSU3263
Response regulator, PilZ domain-containing; Domains: REC, PilZ.
 
 
 0.745
GSU1220
Response regulator, GspIIEN domain-containing; Domains: GspIIEN, REC.
 
 
 
 0.744
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.