STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilRSigma-54-dependent transcriptional response regulator PilR; Domains: REC, sigma54 interaction, HTH8. (458 aa)    
Predicted Functional Partners:
pilS
Sensor histidine kinase PilS, PAS domain-containing; Domains: PAS, HisKA, HATPase_c.
 
 0.994
rpoN
RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.978
pilC
Type IV pilus inner membrane protein PilC.
  
  
 0.888
pilT-4
Twitching motility pilus retraction protein.
  
  
 0.824
pilB
Type IV pilus biogenesis ATPase PilB.
  
  
 0.786
gnfL
Nitrogen fixation master sensor histidine kinase, PAS domain-containing; Domains: PAS, HisKA, HATPase_c.
 
 0.698
ribF
Riboflavin kinase and FAD synthetase; Belongs to the ribF family.
  
  
 0.671
pilA-N
Geopilin domain 1 protein.
  
  
 0.638
pilA-C
Geopilin domain 2 protein.
  
  
 0.628
pilT-2
Twitching motility pilus retraction protein.
      
 0.599
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.