STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cimACitramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway; Belongs to the alpha-IPM synthase/homocitrate synthase family. (528 aa)    
Predicted Functional Partners:
leuD
Isopropylmalate/citramalate isomerase, small subunit; Belongs to the LeuD family.
 
 
 0.990
leuC
Isopropylmalate/citramalate isomerase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.990
ilvD
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
 
 
 0.982
ilvE
Branched-chain amino acid aminotransferase.
  
 0.975
por
Pyruvate:ferredoxin/flavodoxin oxidoreductase.
  
 
 0.964
ilvB
Acetolactate synthase, large subunit, biosynthetic type.
 
 
 0.958
accC
acetyl-CoA carboxylase, biotin carboxylase component; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
 0.954
ilvN
Acetolactate synthase, small subunit.
 
 
 0.953
korA
2-oxoglutarate:ferredoxin oxidoreductase, alpha subunit.
   
 
 0.938
korB
2-oxoglutarate:ferredoxin oxidoreductase, thiamin diphosphate-binding subunit.
   
 
 0.935
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.