Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSU1983Protein tyrosine kinase, putative. (309 aa)    
Predicted Functional Partners:
GSU1984
Polysaccharide chain length determinant protein.
  
 0.960
GSU1985
Periplasmic polysaccharide biosynthesis/export protein.
 
 
 0.948
GSU1986
Undecaprenyl-phosphate glycosylphosphotransferase.
 
  
 0.944
nuoBCD
NADH dehydrogenase I, B/C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 20 kDa subunit family. In the C-terminal section; belongs to the complex I 49 [...]
     
 0.900
GSU1849
Hypothetical protein.
  
  
 0.892
epsH
Exopolysaccharide synthesis membrane protein H (exosortase).
 
    0.864
GSU1982
ATPase, putative.
 
    0.861
GSU1980
Polysaccharide deacetylase and DUF3473 domain protein.
 
    0.850
hoxF
Bidirectional NAD-reducing hydrogenase, diaphorase subunit.
     
 0.838
GSU1981
Hypothetical protein.
 
  
 0.767
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: high (90%) [HD]