close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSU2016Sensor diguanylate cyclase/phosphodiesterase, PAS domain-containing; Domains: PAS, GGDEF, EAL. (799 aa)    
Predicted Functional Partners:
GSU1655
Response receiver sensor histidine kinase response regulator, PAS and GAF domain-containing; Domains: REC, PAS, GAF, HisKA, HATPase_c, REC.
 
 
 0.981
GSU0149
Motility response receiver histidine kinase; Domains: REC, HisKA, HATPase_c.
 
 
 0.960
GSU1007
Sensor cyclic diguanylate phosphodiesterase, GAF and GAF domain-containing; Domains: GAF, GAF, HD-GYP.
 
 
 0.953
GSU0537
Sensor diguanylate cyclase/phosphodiesterase, PAS domain-containing; Domains: PAS, GGDEF, EAL.
 
 
0.951
GSU1302
Sensor histidine kinase response regulator, HAMP domain-containing, putative heme-binding site; Domains: HAMP, HisKA, HATPase_c, REC.
 
 
 0.949
GSU1555
Sensor histidine kinase response regulator, 5TM, PAS, PAS, GAF and PAS domain-containing; Domains: 5TM, PAS, PAS, GAF, PAS, HisKA, HATPase_c, REC.
  
 
 0.949
GSU2511
Sensor diguanylate cyclase/phosphodiesterase, CHASE4 and PAS domain-containing; Domains: CHASE4, PAS, GGDEF, EAL.
 
 
0.944
GSU3263
Response regulator, PilZ domain-containing; Domains: REC, PilZ.
  
 
 0.937
GSU1265
Sensor histidine kinase response regulator; Domains: HisKA, HATPase_c, REC.
 
 
 0.932
GSU2314
Sensor histidine kinase response regulator; Domains: DUF3365, PAS, PAS, HisKA, HATPase_c, REC, Hpt.
 
 
 0.932
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.