Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GSU2144Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c. (456 aa)    
Predicted Functional Partners:
GSU2145
Winged-helix transcriptional response regulator; Domains: REC, trans_reg_C.
 
   0.970
GSU3263
Response regulator, PilZ domain-containing; Domains: REC, PilZ.
 
 
 
 0.844
phoB
Winged-helix phosphate transcriptional response regulator; Domains: REC, trans_reg_C.
 
   0.833
cheY40H-2
Response receiver CheY associated with MCPs of class 40H.
  
   0.830
GSU0008
Response receiver sensor histidine kinase, PAS domain-containing; Domains: REC, PAS, HisKA, HATPase_c.
 
 
0.824
GSU3118
Winged-helix transcriptional response regulator; Domains: REC, trans_reg_C.
  
   0.822
GSU1220
Response regulator, GspIIEN domain-containing; Domains: GspIIEN, REC.
  
   0.821
GSU2314
Sensor histidine kinase response regulator; Domains: DUF3365, PAS, PAS, HisKA, HATPase_c, REC, Hpt.
 
 
0.818
GSU2046
Response regulator; Domains: REC.
  
   0.815
GSU1879
Winged-helix transcriptional response regulator; Domains: REC, trans_reg_C.
  
   0.806
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.