Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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[Homology]
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GSU2145Winged-helix transcriptional response regulator; Domains: REC, trans_reg_C. (232 aa)    
Predicted Functional Partners:
GSU2144
Sensor histidine kinase, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c.
 
   0.970
GSU1302
Sensor histidine kinase response regulator, HAMP domain-containing, putative heme-binding site; Domains: HAMP, HisKA, HATPase_c, REC.
 
 
 0.889
nuoBCD
NADH dehydrogenase I, B/C/D subunits; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 20 kDa subunit family. In the C-terminal section; belongs to the complex I 49 [...]
   
   0.869
GSU0149
Motility response receiver histidine kinase; Domains: REC, HisKA, HATPase_c.
 
 
 0.828
GSU2947
Sensor histidine kinase, HAMP domain-containing; Member of a two-component regulatory system.
 
 
 0.822
GSU3138
Response receiver histidine kinase; Domains: REC, HisKA, HATPase_c.
 
 
 0.817
GSU3518
Sensor histidine kinase; Domains: HisKA, HATPase_c.
 
 
 0.810
GSU1555
Sensor histidine kinase response regulator, 5TM, PAS, PAS, GAF and PAS domain-containing; Domains: 5TM, PAS, PAS, GAF, PAS, HisKA, HATPase_c, REC.
 
 
 0.808
GSU3263
Response regulator, PilZ domain-containing; Domains: REC, PilZ.
 
 
0.803
GSU1878
Sensor histidine kinase; Domains: HisKA, HATPase_c.
 
 
 0.794
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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