STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metY-2O-acetyl-L-homoserine sulfhydrylase. (427 aa)    
Predicted Functional Partners:
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 
 0.990
metH
5-methyltetrahydrofolate--homocysteine S-methyltransferase, cobalamin-dependent.
  
 
 0.949
metF-2
5-methyltetrahydrofolate--homocysteine S-methyltransferase and 5,10-methylenetetrahydrofolate reductase.
  
 
 0.948
metC-2
Cystathionine gamma-synthase/beta-lyase.
 
 
0.937
metC-1
Cystathionine gamma-synthase/beta-lyase.
 
 
0.934
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.913
metY-1
O-acetyl-L-homoserine sulfhydrylase.
  
  
0.905
hom
Homoserine dehydrogenase.
  
 
 0.856
cysK
Cysteine synthase A.
    
 0.833
tdcB
Threonine and serine dehydratase and deaminase, catabolic; Catalyzes the conversion of threonine to 2-oxobutanoate and ammonia. Functions in the threonine-dependent pathway of isoleucine biosynthesis, which is the minor pathway for isoleucine biosynthesis in G.sulfurreducens. Also displays serine ammonia-lyase activity, yielding pyruvate from L-serine; Belongs to the serine/threonine dehydratase family.
   
 
  0.810
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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