Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
metY-2O-acetyl-L-homoserine sulfhydrylase. (427 aa)    
Predicted Functional Partners:
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 
 0.991
metH
5-methyltetrahydrofolate--homocysteine S-methyltransferase, cobalamin-dependent.
  
 
 0.950
metF-2
5-methyltetrahydrofolate--homocysteine S-methyltransferase and 5,10-methylenetetrahydrofolate reductase.
  
 
 0.950
metC-2
Cystathionine gamma-synthase/beta-lyase.
 
 
0.935
metC-1
Cystathionine gamma-synthase/beta-lyase.
 
 
0.926
metK-1
ATP--methionine S-adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
 
 0.917
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.912
metY-1
O-acetyl-L-homoserine sulfhydrylase.
  
 
0.905
metK-2
ATP--methionine S-adenosyltransferase.
   
 
  0.900
hom
Homoserine dehydrogenase.
  
 
 0.858
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.