Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cbiLCobalt-sirohydrochlorin C20-methyltransferase; Belongs to the precorrin methyltransferase family. (236 aa)    
Predicted Functional Partners:
cbiH/cbiP
Cobalt-precorrin-3 C17-methyltransferase and adenosylcobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.998
cbiG
cobalt-precorrin-5A hydrolase.
  
 0.998
cbiF
Cobalt-precorrin-4 C11-methyltransferase.
 
  
 0.998
cbiET
cobalt-precorrin-6B C5,C15-methyltransferase and C12-decarboxylase.
 
  
 0.995
cbiC
cobalt-precorrin-8X methylmutase.
 
  
 0.993
cbiD
cobalt-precorrin-5B C1-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.988
cysG
Precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase, putative.
 
  
 0.980
cbiA
cob(II)yrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.979
hemD
Uroporphyrinogen III C2,C7-methyltransferase and uroporphyrinogen III synthase.
 
 
 0.971
cbiX
Sirohydrochlorin cobaltochelatase.
 
 
 0.947
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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