node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GSU1694 | GSU2289 | GSU1694 | GSU2289 | HAD superfamily hydrolase. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.909 |
GSU1694 | cinA | GSU1694 | GSU0143 | HAD superfamily hydrolase. | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | 0.920 |
GSU1694 | nadC | GSU1694 | GSU1936 | HAD superfamily hydrolase. | Quinolinate phosphoribosyltransferase, decarboxylating; Belongs to the NadC/ModD family. | 0.900 |
GSU1694 | nadD | GSU1694 | GSU3210 | HAD superfamily hydrolase. | Nicotinate/nicotinamide mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.914 |
GSU1694 | nudC | GSU1694 | GSU1044 | HAD superfamily hydrolase. | NADH pyrophosphatase. | 0.902 |
GSU1694 | surE | GSU1694 | GSU1523 | HAD superfamily hydrolase. | Nucleoside 3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.913 |
GSU2289 | GSU1694 | GSU2289 | GSU1694 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | HAD superfamily hydrolase. | 0.909 |
GSU2289 | cinA | GSU2289 | GSU0143 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | 0.957 |
GSU2289 | nadC | GSU2289 | GSU1936 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Quinolinate phosphoribosyltransferase, decarboxylating; Belongs to the NadC/ModD family. | 0.948 |
GSU2289 | nadD | GSU2289 | GSU3210 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate/nicotinamide mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.945 |
GSU2289 | nadE | GSU2289 | GSU0652 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.627 |
GSU2289 | nudC | GSU2289 | GSU1044 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NADH pyrophosphatase. | 0.924 |
GSU2289 | surE | GSU2289 | GSU1523 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nucleoside 3'/5'-monophosphate phosphatase and short-chain exopolyphosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.905 |
cinA | GSU1694 | GSU0143 | GSU1694 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | HAD superfamily hydrolase. | 0.920 |
cinA | GSU2289 | GSU0143 | GSU2289 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.957 |
cinA | nadC | GSU0143 | GSU1936 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | Quinolinate phosphoribosyltransferase, decarboxylating; Belongs to the NadC/ModD family. | 0.945 |
cinA | nadD | GSU0143 | GSU3210 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | Nicotinate/nicotinamide mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.961 |
cinA | nadE | GSU0143 | GSU0652 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.576 |
cinA | nudC | GSU0143 | GSU1044 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | NADH pyrophosphatase. | 0.924 |
cinA | rsfS | GSU0143 | GSU3209 | Molybdopterin-binding domain nicotinamide nucleotide amidohydrolase, putative; Belongs to the CinA family. | Protein of unknown function DUF143; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.429 |