Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GSU3370Helix-turn-helix transcriptional regulator, GntR family. (235 aa)    
Predicted Functional Partners:
ilvN
Acetolactate synthase, small subunit.
   
    0.674
GSU2354
Helix-turn-helix transcriptional regulator, IclR family.
  
  
 0.592
GSU0514
Helix-turn-helix transcriptional regulator, IclR family.
  
  
 0.591
GSU1072
Helix-turn-helix transcriptional regulator, IclR family.
  
  
 0.587
GSU3109
Helix-turn-helix transcriptional regulator, IclR family.
  
  
 0.572
putA
Proline dehydrogenase and Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
     
 0.520
GSU3371
TIM barrel protein, AP endonuclease family 2/xylose isomerase-like family.
  
    0.494
birA
Biotin operon repressor and biotin--acetyl-CoA carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
     
 0.458
hemK
Peptide chain release factor methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
   
   0.455
GSU2057
TRAP transporter, large membrane protein component.
 
    0.453
Your Current Organism:
Geobacter sulfurreducens
NCBI taxonomy Id: 243231
Other names: G. sulfurreducens PCA, Geobacter sulfurreducens PCA, Geobacter sulfurreducens str. PCA, Geobacter sulfurreducens strain PCA
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