node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GSU1796 | GSU3541 | GSU1796 | GSU3541 | DHH domain phosphoesterase, putative. | Hypothetical protein. | 0.472 |
GSU1796 | rdgB | GSU1796 | GSU1794 | DHH domain phosphoesterase, putative. | Xanthosine/inosine triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.717 |
GSU1796 | rph | GSU1796 | GSU1795 | DHH domain phosphoesterase, putative. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.730 |
GSU1797 | GSU3541 | GSU1797 | GSU3541 | ComEA-related DNA-binding/uptake protein. | Hypothetical protein. | 0.488 |
GSU1797 | cimA | GSU1797 | GSU1798 | ComEA-related DNA-binding/uptake protein. | Citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.820 |
GSU3541 | GSU1796 | GSU3541 | GSU1796 | Hypothetical protein. | DHH domain phosphoesterase, putative. | 0.472 |
GSU3541 | GSU1797 | GSU3541 | GSU1797 | Hypothetical protein. | ComEA-related DNA-binding/uptake protein. | 0.488 |
GSU3541 | cimA | GSU3541 | GSU1798 | Hypothetical protein. | Citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.491 |
GSU3541 | rdgB | GSU3541 | GSU1794 | Hypothetical protein. | Xanthosine/inosine triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.416 |
GSU3541 | rph | GSU3541 | GSU1795 | Hypothetical protein. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.416 |
cimA | GSU1797 | GSU1798 | GSU1797 | Citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway; Belongs to the alpha-IPM synthase/homocitrate synthase family. | ComEA-related DNA-binding/uptake protein. | 0.820 |
cimA | GSU3541 | GSU1798 | GSU3541 | Citramalate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate. Makes part of the main pathway for isoleucine biosynthesis in G.sulfurreducens, i.e. the citramalate-dependent pathway; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Hypothetical protein. | 0.491 |
rdgB | GSU1796 | GSU1794 | GSU1796 | Xanthosine/inosine triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | DHH domain phosphoesterase, putative. | 0.717 |
rdgB | GSU3541 | GSU1794 | GSU3541 | Xanthosine/inosine triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypothetical protein. | 0.416 |
rdgB | rph | GSU1794 | GSU1795 | Xanthosine/inosine triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.994 |
rph | GSU1796 | GSU1795 | GSU1796 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | DHH domain phosphoesterase, putative. | 0.730 |
rph | GSU3541 | GSU1795 | GSU3541 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Hypothetical protein. | 0.416 |
rph | rdgB | GSU1795 | GSU1794 | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | Xanthosine/inosine triphosphate pyrophosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.994 |