STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0001Aspartate aminotransferase (aspB1); Similar to PID:1146246 SP:P53001 GB:AL009126 percent identity: 44.38; identified by sequence similarity; putative; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. (375 aa)    
Predicted Functional Partners:
pheA
Chorismate mutase/prephenate dehydratase (pheA); Similar to SP:P43909 PID:683585 percent identity: 38.59; identified by sequence similarity; putative.
 
 0.992
hisC
Histidinol-phosphate aminotransferase (hisC); Similar to SP:P06986 GB:U02071 GB:X03416 PID:41695 PID:41710 percent identity: 29.00; identified by sequence similarity; putative.
 
 
0.935
argG
Argininosuccinate synthetase (argG); Similar to GB:M21315 SP:P13256 PID:150046 percent identity: 71.90; identified by sequence similarity; putative; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
 0.932
mdh
L-lactate dehydrogenase EGAD|7256|705; Catalyzes the reversible oxidation of (S)-malate and (S)- sulfolactate to oxaloacetate and sulfopyruvate, respectively. Can use both NADH and NADPH, although activity is higher with NADPH. Oxidation of (S)-sulfolactate is observed only in the presence of NADP(+). Can also oxidize tartrate. Cannot reduce pyruvate, nor alpha-ketoglutarate. Belongs to the LDH/MDH superfamily.
  
 0.931
purA
Adenylosuccinate synthetase (purA); Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 0.926
MJ_0612
Chorismate mutase/prephenate dehydratase (tyrA); Similar to SP:P07023 PID:457110 GB:U00096 PID:1788952 percent identity: 33.46; identified by sequence similarity; putative; In the N-terminal section; belongs to the prephenate/arogenate dehydrogenase family.
    
 0.921
mfnA
Group II decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
  
 
 0.920
argJ
Glutamate N-acetyltransferase (argJ); Catalyzes only the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor. Belongs to the ArgJ family.
  
 
 0.919
MJ_1056
Asparagine synthetase (asnB); Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277 percent identity: 32.95; identified by sequence similarity; putative; Belongs to the asparagine synthetase family.
  
 
 0.916
MJ_1116
Asparagine synthetase (asnB); Similar to GB:J05554 SP:P22106 PID:145393 GB:U00096 PID:1651277 percent identity: 33.78; identified by sequence similarity; putative; Belongs to the asparagine synthetase family.
  
 
 0.916
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.