Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_00072-hydroxyglutaryl-CoA dehydratase, subunit beta (hgdB); Similar to GB:X14252 SP:P11570 PID:38802 percent identity: 22.79; identified by sequence similarity; putative. (373 aa)    
Predicted Functional Partners:
MJ_0004
(R)-2-hydroxyglutaryl-CoA dehydratase activator; Similar to SP:P11568 GB:X59645 PID:433932 percent identity: 37.70; identified by sequence similarity; putative.
 
 0.997
MJ_0800
(R)-2-hydroxyglutaryl-CoA dehydratase activator; Similar to SP:P11568 GB:X59645 PID:433932 percent identity: 31.78; identified by sequence similarity; putative.
 
 0.924
MJ_0011
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0011.
 
    0.699
MJ_0008
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0008.
  
    0.618
MJ_0990
Conserved hypothetical protein; Similar to GB:L13279 SP:P31065 PID:290415 GB:U00096 PID:1788239 percent identity: 39.13; identified by sequence similarity; putative; Belongs to the sulfur carrier protein TusA family.
  
    0.597
MJ_0009
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0009.
  
    0.596
apgM2
BcpC phosphonopyruvate decarboxylase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
    0.580
MJ_0989
Conserved hypothetical protein; Similar to SP:P39164 GB:U00096 PID:1787471 percent identity: 28.95; identified by sequence similarity; putative; To M.kandleri MK0008.
  
    0.489
MJ_0003
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0003.
 
     0.479
queE
Coenzyme PQQ synthesis protein III isolog (Haemophilus influenzae}; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
    0.421
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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