STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frhDCoenzyme F420-reducing hydrogenase, delta subunit (frcD); Similar to GB:X61202 PID:44706 percent identity: 65.70; identified by sequence similarity; putative; Belongs to the peptidase A31 family. (183 aa)    
Predicted Functional Partners:
frhG
Coenzyme F420-reducing hydrogenase, gamma subunit; Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
 
 
 0.999
frhB
Coenzyme F420-reducing hydrogenase, beta subunit (frhB); Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen. Belongs to the FrhB family.
 
 
 0.990
MJ_0725
Coenzyme F420-reducing hydrogenase, beta subunit; Similar to GB:J02914 SP:P19499 PID:149718 GB:AE000666 percent identity: 42.24; identified by sequence similarity; putative; Belongs to the FrhB family.
 
 
 0.963
MJ_0727
Coenzyme F420-reducing hydrogenase, alpha subunit; Similar to GB:J02914 SP:P19496 PID:551889 GB:AE000666 percent identity: 27.08; identified by sequence similarity; putative.
 
 0.962
MJ_0726
Coenzyme F420-reducing hydrogenase, gamma subunit; Similar to GB:X61201 PID:809730 SP:Q00393 percent identity: 43.53; identified by sequence similarity; putative; Belongs to the FrhG family.
 
 
 0.940
MJ_1349
Coenzyme F420-reducing hydrogenase, beta subunit; Similar to GB:X61201 PID:809731 SP:Q00391 percent identity: 35.74; identified by sequence similarity; putative; Belongs to the FrhB family.
 
 
 0.931
mer
N5,N10-methylene-tetrahydromethanopterin reductase (mer); Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
  
 
 0.922
MJ_0253
Coenzyme F420-reducing hydrogenase, delta subunit (frcD); Similar to GB:X61201 PID:44702 percent identity: 45.45; identified by sequence similarity; putative; Belongs to the peptidase A31 family.
  
  
 
0.903
mtd
N5,N10-methylene-tetrahydromethanopterin dehydrogenase (mtd); Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
     
 0.902
ileS
isoleucyl-tRNA synthetase (ileS); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
   0.724
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.