Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MJ_0043Intein containing hypothetical protein; Similar to GP:1303985 percent identity: 41.38; identified by sequence similarity; putative. (785 aa)    
Predicted Functional Partners:
thiL
Thiamine monphosphate kinase (thiL); Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.685
nop10
Conserved hypothetical protein; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA; Belongs to the NOP10 family.
       0.685
eif2a
Translation initiation factor aIF-2, subunit alpha (aif2A); eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Belongs to the eIF-2-alpha family.
       0.685
rpl44e
LSU ribosomal protein L44E; Binds to the 23S rRNA.
       0.685
rps27e
SSU ribosomal protein S27E; Similar to SP:P35997 SP:P38711 PID:2131116 PID:486271 PID:500694 percent identity: 42.59; identified by sequence similarity; putative.
       0.685
MJ_0305
Conserved hypothetical protein; Similar to GP:1787876 percent identity: 27.99; identified by sequence similarity; putative.
       0.685
MJ_1210
Conserved hypothetical protein; Similar to GB:AE000782 percent identity: 46.03; identified by sequence similarity; putative.
       0.685
MJ_0538
Hypothetical protein; Identified by GeneMark; putative; M. jannaschii predicted coding region MJ0538.
       0.649
MJ_0808
Pyruvate-formate-lyase-activating enzyme (act); Similar to PID:1072362 SP:Q46267 percent identity: 30.41; identified by sequence similarity; putative.
       0.649
priS
DNA primase, putative; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May [...]
       0.648
Your Current Organism:
Methanocaldococcus jannaschii
NCBI taxonomy Id: 243232
Other names: M. jannaschii DSM 2661, Methanocaldococcus jannaschii DSM 2661, Methanocaldococcus jannaschii str. DSM 2661, Methanococcus jannaschii DSM 2661
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.